2 The goal of diabetes treatment in adolescents is to maintain blood glucose level within the normal range without recurrent or severe hypoglycemia that is, a balance between hyperglycemia treatment and minimizing the frequency of hypoglycemic episodes should be maintained. In severe cases, changes in brain metabolism can even cause permanent sequelae and be potentially life-threatening. It is well known that hypoglycemia causes cognitive impairment and mood changes, such as depression, irritation, and fear. 1Įarly glycemic control is particularly important for preventing the development and progression of chronic complications of diabetes. According to the latest nationwide population-based registry study, the estimated incidence of T1D per 100,000 person-years for all ages in China was 1.01. Type 1 diabetes mellitus (T1D) is an autoimmune disease in which immune cells attack and destroy insulin-producing pancreatic β cells. Keywords: WeChat, type 1 diabetes, self-management, glycated hemoglobin A1c
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Trial Registration: This study was registered at, number ChiCTR1900025495. The DQOL scores in groups B and C decreased significantly from the baseline (both P < 0.05), with no change in group A.Ĭonclusion: Flash glucose monitoring combined with the WeChat-interactive system may help achieve sustained glycemic control and higher satisfaction in patients with juvenile type 1 diabetes. In addition, the DMTSQ scores increased in the 6th month in all groups (all P < 0.05), and the largest rise in scores was found in group C, followed by groups B and A. Hypoglycemic episodes per month decreased from baseline in groups B and C (both P < 0.05) and were more significant in group C ( P < 0.001). Results: After the 6-month intervention, groups B and C showed significantly lower glycated hemoglobin A1c (HbA1c) levels compared to those observed at baseline (both P < 0.05), with the largest decrease observed in group C (group B vs group C, P =0.04). The intergroup differences in demographics, biochemical indicators, and questionnaire scores of the Diabetes Monitoring and Treatment Satisfaction Questionnaire and Diabetes Specific Quality of Life assessment were compared at the baseline and after 6 months. Patients and Methods: A total of 60 juvenile patients with type 1 diabetes were randomly assigned into three groups: a blood glucose self-monitoring group (group A), a flash glucose monitoring (group B), and a flash glucose monitoring combined WeChat-interactive management group (group C). This study aimed to evaluate the efficacy of a novel flash glucose monitoring device combined with the WeChat platform in juvenile type 1 diabetes management.
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Nevertheless, how to combine the strengths of the WeChat platform with traditional medical strategy remains to be explored.
The widespread use of WeChat in China provides an opportunity for self-management practices in patients with diabetes. Purpose: Smartphones have received increasing attention and achieved positive outcomes in diabetes intervention.
*These authors contributed equally to this workĭepartment of Endocrinology and Metabolism, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai Clinical Center for Diabetes, Shanghai Key Clinical Center for Metabolic Disease, Shanghai Diabetes Institute, Shanghai Key Laboratory of Diabetes Mellitus, 600 Yishan Road, Xuhui District, Shanghai, 200233, People’s Republic of ChinaĮmail Yuejie Xu, 1, * Lei Xu, 1, * Weijing Zhao, 1 Qing Li, 1 Ming Li, 1 Wei Lu, 1 Hui Zeng, 1 Jinhua Yan, 2 Daizhi Yang, 2 Wei Wu, 3 Jianping Weng, 2 Jiemin Pan, 1 Fang Liu 1ġDepartment of Endocrinology and Metabolism, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai Clinical Center for Diabetes, Shanghai Key Clinical Center for Metabolic Disease, Shanghai Diabetes Institute, Shanghai Key Laboratory of Diabetes Mellitus, Shanghai, 200233, People’s Republic of China 2Department of Endocrinology and Metabolic Disease, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, 510630, People’s Republic of China 3Department of Pediatrics, Tongji Hospital, Wuhan Tongji Medical University, Wuhan, Hubei, 430030, People’s Republic of China
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